Abstract: An optical coherence tomography system with depth-resolution 8 μm and broadband source (SLD) is implemented. The system has realized depth scanning speed of 160 mm/s and imaging depth of 3 mm using Fourier-domain rapid scanning optical delay line. The OCT images of mildew infecting skin and healthy skin of nude mouse have been obtained. The structures of skin are shown in the images before the pathological changes and after.