Abstract: The defocus and astigmatism of human eye can be treated by using glass and contact lens or by excimer laser, because the human has optical aberration, it can not get best vision even if the human eye has treated the defocus and astigmatism . we analyzed the wave-front aberration interpretation and measurement on the human eye, and use Zernike polynomials to express wave-front aberration ,it will give the theory base for treating human eye wave-front aberration using excimer laser.