Abstract: Objective: Thermal effects of compound cold &cool Chinese herbal medicine on different body parts of rats were studied using the thermal texture maps system. Methods: The decoction made from Rhizoma Anemarrhenae, Gypsum Fibrosum, Radix Gentianae, Cortex Phellodendri were used to fill the stomach of rats for three weeks continuously, then the thermal effects of different body parts were measured using thermal texture maps(TTM)system，The measured time were pre-taking medicine, pro-taking medicine or stop taking medicine one week later, respectively. Results: After filling the stomach with compound cold &cool Chinese herbal medicine, body temperatures of rats in left fore-armpit, right fore-armpit, neck, upper abdomen and middle abdomen declined obviously, and the temperatures in left fore-armpit、neck、upper abdomen and mid-abdomen were statistically different after taking medicine (p<0.05),but for right fore-armpit, the difference were extremely different(p<0.01).One week after stop taking medicine, the temperatures in all parts kept at low level, they were remarkably different in neck, upper abdomen, middle abdomen, compared with those of pre-taking medicine, and they were conspicuously different in left fore-armpit and right fore-armpit. Temperatures in left later-armpit and right later-armpit fallen after taking medicine for one week, they were statistically different (p<0.05), but they did not obviously fall down after stop taking medicine for three weeks. Temperatures in head and neck kept invariable whether taking medicine or stop taking medicine one week later. During the experiment, all data changed quite little, compared with that of the control.Conclusion: Compound cold & cool Chinese herbal medicine could roll back the temperature for all body parts, but the extents were different, they seemed varying with different body parts.