激光生物学报摘要, 更新时间: 2007年4月15日
  由美国生科集团 (BVTech, Inc.) 主办
  
S波段高功率微波对眼组织结构和功能影响的实验研究
激光生物学报摘要 2007-1

陈 鹏， 梁 洁，马 萍，单 清，闫文华，苏镇涛，孙东翀，钱焕文* （军事医学科学院放射与辐射医学研究所，北京 100850）

摘 要： 目的：研究5 mW/cm2的S波段高功率微波（high-power microwave，HPM）对动物眼的组织结构和功能的影响，为我国高功率微波安全防护标准的制定提供参考。方法：S波段HPM模拟源以远场平面波（平均功率5 mW/cm2）分三个不同的峰值功率（G1、G2、G3组）进行单次照射，并在照后7个时间点，通过眼底镜、裂隙灯观察、视网膜电图测定、组织病理学方法等研究HPM对动物的角膜、晶状体、视网膜等眼重要部位的结构与功能的影响。结果：HPM照射后角膜表面平滑无异常，未见混浊、粗糙等病理现象发生；晶状体在观察期内无肉眼可见的晶状体混浊，实质和晶状体后囊和玻璃体无异常；照射后即刻动物眼底动静脉和毛细血管稍有扩张充血，并于1天～3天后恢复正常表现；病理染色显示G1和G2组照后1天视网膜内外节排列稍有紊乱，照后3天～7天内恢复；G3组稍重，可见外核层细胞排列松散，于照后7天～14天后亦恢复正常；视网膜电图显示与照前相比，三组在照后1天的视网膜电图都有所降低，但3天后即恢复正常，直至照后28天无明显改变。结论：5 mW/cm2的S波段HPM单次照射对角膜、晶状体和玻璃体等部位不能造成损伤，视网膜在照后有轻微病理变化，但很快可以恢复。大鼠眼视功能在照后可出现暂时但可逆性的下降。此剂量范围的HPM照射对眼组织结构和功能无显著影响。


Experimental Research of the Effects on Rat Eye Structure and Function Induced by S-band High-power Microwave Irradiation

CHEN Peng ，LIANG Jie ，MA Ping，SHAN Qing , YAN Wen-hua, SU Zhen-tao , SUN Dong-chong , QIAN Huan-wen* （Institute of Radiation Medicine, Academy of Military Medical Sciences , Beijing 100850 ,China）

Abstract：Objective: This study is to observe the bioeffects of the S wave band high-power Microwave (HPM )on established animal model eyes and provide safety referrence for safety protection of microwave irradiation. Methods: Three different peak value powers were used in this study. After the HMP exposure, naked eye observation and examination with slit-lamp, funduscope , electroretinograms (ERG) and histopathology were carried out at 7 time points to study the effects of HPM on structure and function of ocular organs, such as cornea, lens and retina. Results: After the HPM exposure, lesions were not observed on the corneal surface and the posterior cortex of lens. Degenerative changes of slight degrees occurred in the photo receptor outer segments , inner segments and the outer nuclear layer post irradiation , however, which recovered in one week. In all three groups, the b-wave amplitude of ERG show a temporary statistic difference 1 day after exposure and resume natural level after 2 days. Conclusion:


 

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