激光生物学报摘要, 更新时间: 2007年4月29日
  由美国生科集团 (BVTech, Inc.) 主办
  
采用红外热扫描成像系统研究归胃经寒凉中药对胃热证大鼠的热效应
激光生物学报摘要 2007-2

李小梅1,黄雪群1,李续娥1,曾常春2,郭周义2,郭宝江1 (1.华南师范大学生命科学学院 广东 广州510631;2华南师范大学信息光电子科技学院,广东 广州510631)

摘 要:目的:利用红外热扫描成像(thermal texture maps,TTM)系统探讨归胃经寒凉中药对胃热证大鼠全身不同部位热效应的影响。方法:用干姜水煎剂连续灌胃大鼠(5mg.kg-1.d-1)15天,造成胃热证模型,再分别予以黄连、蒲公英、石斛、枳实4味中药水煎剂分大、小剂量治疗10天,采用TTM仪测定造模及治疗前后大鼠全身各部位的热效应变化情况。结果:与造模前比较,胃热证大鼠的中腹、上腹部温度有非常显著的升高(P<0.01),头、颈、左前腋、胸、温度有显著的升高(P<0.05)。治疗10天后,与胃热证模型组比较,黄连大小剂量组的头、左前腋、胸部及大剂量组的颈部温度显著降低(P<0.05),中腹和上腹部温度非常显著降低(P<0.01);蒲公英大小剂量组的左前腋、胸、中腹、上腹部在治疗后的温度显著降低(P<0.05),而大剂量组的头、颈部在治疗后的温度亦显著降低(P<0.05);石斛大剂量组的左前腋、中腹、上腹部及小剂量组的中腹、上腹部温度在治疗后显著降低(P<0.05);枳实组中,仅大剂量组的左前腋、上腹部温度在治疗后显著降低(P<0.05)。结论:大鼠灌胃干姜煎剂造成胃热证模型后,全身多部位温度明显升高,但经黄连、蒲公英、石斛、枳实这4味寒凉中药治疗后,各部位温度又降低。大鼠体温降低的程度因药物而异,药物寒性越强,温度降低的部位多且程度大;药物寒性弱,则温度降低的部位少、程度低,且对大鼠全身各部位热效应的影响以上腹部及中腹部最为明显。


Thermal Effects of Cold﹠Cool Traditional Chinese Medicine of Channel Tropism of Stomach on Stomach-heat Syndrome Rats Using Thermal Texture Maps System

LI Xiao-meia, HUANG Xue-quna, LI Xu-ea, ZENG Chang-chunb, GUO Zhou-yib, GUO Bao-jianga (South China Normal University a.Life Science College; b.Information Photoelectric Science &Technology College, Guangdong Guangzhou 510631,China)

Abstracts:Objective: Thermal effects of Traditional Chinese medicine of channel tropism of stomach on stomach-heat syndrome rats' different body parts were studied using the thermal texture maps system.. Methods:Decoction made by Rhizoma zingeberis was used to fill the stomach of rats for 15 days at 5mg.kg-1.d-1 in order to modeling stomach-heat syndrome,then decoction made by four Chinese medicine: Rhizoma coptidis, Herbed taraxaci, Herba dendrobii and Fractus aurantii immaturus were usedto therapy the syndrome for 10 days at high and low dosage, thermal effects of different body parts before and after modeling or treatment were measured using the Thermal Texture Maps system。


 

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