Abstract：Objective：To investigate the efficacy of pulse dye laser therapy for the treatment of ulcerated haemangiomas in infant. Methods：Seventy-six children (50 girls, 26 boys) with ulcerated haemangiomas, from our vascular malformation clinic were enrolled in a prospective pulse dye laser treatment protocol from April of 1999 to March of 2006. The mean size of the ulcerated haemangiomas requiring treatment was 22.1 cm2. Lesions were treated with minimal debridement and the Cynosure pulse dye laser with a mean energy of 6.6 J/cm2（5.8 J/cm2～8 J/cm2）per treatment. Lesions were treated in a sequential pattern at 4 week intervals until cutaneous healing or involution of the haemangioma occurred. Results：Sixty-eight of the 76 patients (89.5 %) responded to laser therapy alone with a mean number of 4.0（1~8）treatments. Eight patients with very large haemangiomas required oral steroids (2 mg/kg·d-1～3 mg/kg·d-1) in combination with the pulse dye laser. After failing to improve on steroid therapy, two patients required the addition of interferon to their treatment protocol. The rate of clinical efficiency was 100 %.The mean follow up time is 12 months with no sign of recurrent ulceration or regrowth of the haemangiomas in our study population. Conclusion：Pulse dye laser therapy is a reasonably effective means of resolving the untoward complication of ulceration of haemangiomas.