寺庙大学研究人员发现一种提取于圣约翰麦芽植物(Hypericum perforatum)的新颖蛋白质, p27SJ, 可抑制HIV-1基因表达与复制。即将发表在10月27日 <<基因治疗>>网络版上的这一研究结果表明p27SJ可抑制HIV-1 染色体复制。Kamel Khalili博士说: 研究人员最初检查培养于实验室里的圣约翰麦芽植物萃取物, 是想看他们在体外能否影响细胞生长或脑细胞行为。研究中发现这一萃取物可抑制HIV-1基因表达和在感染细胞内的复制。

Novel Protein In St. John's Wort Found To Suppress HIV-1 Gene Expression A novel protein, p27SJ, extracted from a callus culture of the St. John’s wort plant (Hypericum perforatum) suppresses HIV-1 expression and inhibits its replication, according to researchers at Temple University School of Medicine. Their findings, “p27SJ, a novel protein in St. John’s wort, that suppresses expression of HIV-1 genome,” will be published online in the Oct. 27 issue of Gene Therapy (http://www.nature.com/gt).

(See Story from Temple University)