生科新闻, 更新时间: 2005年9月13日
  由美国生科集团 (BVTech, Inc.) 主办
  
神经化学 (Neurochem) 公司在欧洲开始Alzhemed? 治疗Alzheimer's 疾病的三期临床试验
2005-9-13
  

Azhemed? 是一种口服的小分子有机物,它可以结合可溶性Aβ 肽从而阻止其纤维化,公司希望可抑制Alzheimer's 疾病的进一步发展。大约930名轻度到中度的Alzheimer's 病人将参与此次临床试验。另外,有1052名轻度到中度的Alzheimer's 病人参加的在美国的三期临床试验已经于七月完成病人的登记工作,并已经完成部分试验。


Neurochem Announces Launch of European Phase III Clinical Trial on Alzhemed? For Treatment of Alzheimer's Disease

The multi-centre, randomized, double-blind, placebo-controlled and parallel designed European Phase III clinical trial will investigate the safety and efficacy of Alzhemed? in treating AD, with some 930 mild-to- moderate AD patients taking part in the trial.

In July, Neurochem completed the enrolment of 1052 mild-to-moderate AD patients for its North American Phase III clinical trial on Alzhemed?.

About Alzhemed?

Azhemed? is an orally administered, small organic molecule specifically designed to modify the course of AD by binding to soluble amyloid (B) (A(B)) protein and keeping it in a non-fibrillar form. As reported previously, results of the Phase II trial demonstrated that there were no apparent safety findings of concern in patients treated with Alzhemed? and that the investigational product candidate was well tolerated in individuals with mild-to-moderate AD.

Source:YAHOO
 

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